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Study Reveals Brain Coordination Breakdown Behind OCD Origins

3/22/2026

Summary

Story summary

Researchers from the Hebrew University of Jerusalem and SUNY Stony Brook University found a brain signaling system can regulate another, shedding light on obsessive-compulsive disorder (OCD) origins.
Prof. Joshua Goldberg (Hebrew University of Jerusalem) and Prof. Joshua Plotkin (SUNY Stony Brook University) led a study on dorsal striatum and acetylcholine-triggered serotonin.
The findings indicate OCD arises from breakdown in brain coordination rather than chemical imbalances, as published in Nature Communications.

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Story summary

Researchers from the Hebrew University of Jerusalem and SUNY Stony Brook University found a brain signaling system can regulate another, shedding light on obsessive-compulsive disorder (OCD) origins.
Prof. Joshua Goldberg (Hebrew University of Jerusalem) and Prof. Joshua Plotkin (SUNY Stony Brook University) led a study on dorsal striatum and acetylcholine-triggered serotonin.
The findings indicate OCD arises from breakdown in brain coordination rather than chemical imbalances, as published in Nature Communications.