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Study Links Lunges and Squats to Brain Health

3/26/2026

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Story summary
  • A study published in the journal Cell suggests that lunges and squats may protect the brain from aging and dementia.
  • Researchers found that exercise triggers the liver protein GPLD1, which strengthens the blood-brain barrier.
  • In mice, higher GPLD1 levels improved memory and learning, even without exercise.
  • Experts caution that results in mice may not directly translate to humans and emphasize that exercise remains crucial, with plans for human studies underway.