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Story summary
- Johns Hopkins University researchers report that parathyroid hormone (PTH), used to treat bone loss, may address chronic back pain by preventing pain-sensing nerves from invading damaged spinal areas.
- The mechanism is that PTH triggers Slit3 production, which repels those nerve fibers.
- The findings could shift treatment from symptom management to addressing underlying spinal degeneration, though researchers note limitations and publication in Bone Research.
