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Baxdrostat Lowers Blood Pressure in Resistant Patients by 10 mmHg

4/4/2026

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Story summary
  • Baxdrostat reduced blood pressure in patients unresponsive to existing treatments in a Phase III trial led by Professor Bryan Williams at University College London (UCL).
  • The nearly 800-participant study showed a 9–10 mmHg drop after 12 weeks.
  • About 40% reached healthy blood pressure, compared with under 20% on placebo.
  • Findings were presented at the European Society of Cardiology Congress 2025 and published in the New England Journal of Medicine.