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Story summary
- Researchers at the University of California, San Francisco (UCSF) identified FTL1 as a key driver of brain aging, especially in the hippocampus.
- In mice, older animals showed higher FTL1 levels, leading to fewer neuron connections and poorer cognitive performance.
- Reducing FTL1 in older mice reversed these impairments, improving neuron connectivity and memory test results.
- The findings indicate potential FTL1-targeted treatments with support from the National Institutes of Health (NIH).
