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ARPA-H Reports Promising Osteoarthritis Advances, Human Trials Ahead

4/7/2026

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Story summary
  • Advanced Research Projects Agency for Health (ARPA-H) announced promising osteoarthritis developments affecting 32 million Americans.
  • Three years after launching a project, ARPA-H reported progress by teams from Duke University, the University of Colorado, and Columbia University.
  • Teams are pursuing injections and infusions to regrow bone and cartilage for various joints.
  • Testing has occurred only in animals, and experts call findings hugely promising, with human trials to begin within 18 months.