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Long-Term Obesity Raises Heart Disease Risk by 60%

4/10/2026

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Story summary
  • A Mass General Brigham study finds that the duration of overweight status markedly increases heart disease risk.
  • The analysis included 136,498 participants and linked prolonged high-weight exposure to greater cardiovascular risk.
  • Younger adults, especially women under 35, face a 60% higher risk of heart disease due to long-term obesity.
  • The study, published in PLOS One and funded by Eli Lilly, urges early weight management in one's 20s or 30s.