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LSD and Psilocybin Boost Brain Connectivity, Study Finds

4/10/2026

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Story summary
  • A Nature Medicine study analyzed over 500 brain scans from 267 individuals across five countries to show that LSD and psilocybin increase communication between brain regions that normally operate independently.
  • The findings may explain the emotional and visual experiences reported by users.
  • Manesh Girn, the study's lead author, urged reliable benchmarks to assess these drugs as they move toward medical use.