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Story summary
- Case Western Reserve University researchers have found a link between gut bacteria and brain damage in ALS and FTD.
- Certain bacterial sugars trigger immune responses that harm brain cells.
- Among 23 ALS/FTD patients, 70% had elevated harmful glycogen, vs one-third of healthy individuals.
- The findings suggest gut bacteria may influence disease development in at-risk individuals, especially with the C90RF72 mutation.
- Clinical trials on glycogen degradation could start within a year.
