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New Guidelines Warn Against Fish Oil for Cholesterol

4/13/2026

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Story summary
  • New medical guidelines recommend against using fish oil and other over-the-counter supplements to manage cholesterol.
  • The guidelines say these supplements do not significantly lower LDL cholesterol.
  • They may worsen heart health by raising LDL levels and increasing the risk of atrial fibrillation.
  • Prescription fish oil remains recommended for certain high-risk patients.
  • Even as more than half of U.S. adults take supplements for heart health, statins remain more effective at reducing cardiovascular risk.