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Study Finds 50% Report Side Effects from GLP-1 Drugs

4/14/2026

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Story summary
  • A study analyzed more than 400,000 Reddit posts to identify side effects of GLP-1 receptor agonists.
  • Nearly half of users reported side effects, including menstrual irregularities in 4% and psychiatric symptoms in 13%.
  • Neil Sehgal of the University of Pennsylvania led the study, highlighting real-world data over clinical trials.
  • Limitations include Reddit’s skewed demographics and the study cannot prove causation.