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Syphilis Infections Surge 80%, Linked to Heart Risks

4/17/2026

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Story summary
  • Syphilis infections in the United States rose more than 80% from 2018 to 2023.
  • A study in JAMA Network Open finds untreated syphilis raises cardiovascular risk, including a 92% higher stroke risk and a 31% higher heart attack risk.
  • Tulane University researchers tracked nearly 1,500 syphilis patients over 15 years and found heart health complications.
  • The study cannot prove causation, but it urges awareness among clinicians about syphilis’ cardiovascular risks.