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Story perspectives

Long-term Diphenhydramine Use Linked to Cognitive Decline

4/18/2026

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Story summary
  • Diphenhydramine, an antihistamine recommended during pregnancy, initially helped the woman sleep for hours but long-term use worsened insomnia and caused memory problems.
  • After consulting a doctor, she stopped taking the medication because it contributed to her symptoms.
  • Although she still faces insomnia, she has adopted healthier coping strategies and regained mental clarity.
  • Experts warn that prolonged use of such medications can lead to cognitive decline, underscoring the need for caution.