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Gene Therapy Restores Hearing in 90% of Patients

4/22/2026

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Story summary
  • A Nature study by Mass General Brigham and Fudan University reports that a gene therapy targeting the OTOF gene restored significant hearing in 90% of 42 participants within weeks.
  • The therapy was delivered via a harmless virus and produced lasting improvements noted for over two years.
  • Researchers say the treatment could enable speech development and plan to explore its application for other types of hearing loss.