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Protegrin Gum Cuts Harmful Bacteria, 93% HPV Drop

4/23/2026

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Story summary
  • Scientists added protegrin to gum, cutting P. gingivalis and F. nucleatum.
  • HNSCC patients' samples showed a 93% HPV drop while rinses fell 80%.
  • The gum spared beneficial oral bacteria, unlike radiation that harms them, raising Candida.
  • The study, funded by National Institutes of Health (NIH) 5-R01-HL 107904-13, University of California, Los Angeles (UCLA) Academic Senate and National Cancer Institute (NCI) P30 CA168524, calls for trials of the gum as a cancer adjunct.