Trump Signs Executive Order to Accelerate Ibogaine Research for Veterans

On April 18, 2026, President Donald Trump signed an executive order aimed at expediting research into ibogaine, a psychedelic drug derived from the African shrub Tabernanthe iboga. This initiative is particularly focused on addressing mental health issues among veterans, including post-traumatic stress disorder (PTSD), traumatic brain injury, depression, anxiety, and opioid addiction. The order allocates approximately $50 million in federal funding to support research and clinical trials, with the Food and Drug Administration (FDA) instructed to remove regulatory barriers that have historically hindered studies of psychedelic substances.

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The executive order directs federal agencies to prioritize clinical trials and improve coordination in research efforts. FDA Commissioner Dr. Marty Makary indicated that ibogaine could soon be on track for FDA approval, with expedited review processes in place. The order also allows for the drug to be administered under the "Right to Try" law, which permits terminally ill patients to access experimental treatments not yet fully approved by the FDA.

CNN

Ibogaine has been classified as a Schedule I substance since 1967, meaning it is considered to have no accepted medical use and a high potential for abuse. Despite this classification, recent studies have suggested that ibogaine may significantly alleviate symptoms of PTSD and other mental health conditions. A 2024 Stanford University study found that ibogaine treatment led to an average reduction of 88% in PTSD symptoms among veterans.

CNN

The executive order has garnered support from various advocates, including veterans' organizations and public figures like podcaster Joe Rogan and former Texas Governor Rick Perry. Rogan played a pivotal role in bringing ibogaine to Trump's attention, reportedly texting the president about its potential benefits. During the signing ceremony, Trump emphasized the urgency of addressing the mental health crisis among veterans, stating, “Since 9/11, we’ve lost over 21 times more veteran lives to suicide than on the battlefield.”

NewsNation

While the initiative has been met with enthusiasm, it has also raised concerns regarding the safety and efficacy of ibogaine. Critics argue that the drug carries significant risks, including potential cardiac complications. Dr. Arnt Schellekens, a researcher studying ibogaine, cautioned that while early results are promising, more rigorous research is necessary to fully understand the drug's safety profile. Additionally, some experts worry that the expedited process could prioritize speed over thorough scientific evaluation.

CNN

The response to Trump's executive order has been mixed. While some experts express optimism about the potential for new treatments, others highlight the need for more comprehensive studies before widespread implementation. Concerns have also been raised about the potential commercialization of psychedelic treatments and the implications for Indigenous communities that have historically used these substances.

The Jerusalem Post

The executive order marks a significant shift in the U.S. government's approach to psychedelic research, potentially paving the way for broader acceptance and use of these substances in medical settings. As federal agencies begin to implement the order, the first human trials of ibogaine in the United States are anticipated, with researchers eager to explore its therapeutic potential further.

CNN

• “Today’s order will ensure that people suffering from debilitating symptoms might finally have a chance to reclaim their lives and lead a happier life.” — President Donald Trump

Trump just dropped $50M for research into drug banned for decades after text from Joe Rogan

• “If these turn out to be as good as people are saying, it’s going to have a tremendous impact.” — President Donald Trump

Trump Executive Order Fast-Tracks Psychedelic Research

• “We owe it to our war fighters and veterans to turn over every stone” — Health Secretary Robert F. Kennedy Jr.

Military Times

• “And it could open up a lot of research possibilities. It is kind of an exciting time.” — Dr. Kirsten Cherian, Stanford University researcher

CNN

This executive order represents a pivotal moment in the evolving landscape of mental health treatment, particularly for veterans seeking alternative therapies.

Newsday