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Christina Applegate Hospitalized, Receives Support from Co-Stars

4/26/2026

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Story summary
  • Actress Christina Applegate was hospitalized in Los Angeles late last month.
  • Applegate, diagnosed with multiple sclerosis in 2021, has spoken publicly about the condition.
  • Ed O’Neill texted Applegate immediately, offering love and help.
  • Katey Sagal, Linda Cardellini, Will Ferrell and Jean Smart also sent supportive messages.
  • Applegate updated Instagram earlier this month, saying she feels better every day, while representatives for her, O’Neill and Sagal declined comment.