Story perspectives

Dome Membrane Found at T-Cell Synapse, Boosts Immunotherapy

5/9/2026

Summary

Story summary

Scientists used cryo-expansion microscopy to reveal a dome-shaped membrane at the immune synapse of cytotoxic T cells.
Researchers at the University of Geneva and Lausanne University Hospital visualized nanometer-scale immune synapses in human tumor samples.
The dome structure appears linked to adhesion interactions and internal organization of the immune cell.
The study, published in Cell Reports on 1 April 2026, could guide development of improved immuno-oncology therapies.

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Story summary

Scientists used cryo-expansion microscopy to reveal a dome-shaped membrane at the immune synapse of cytotoxic T cells.
Researchers at the University of Geneva and Lausanne University Hospital visualized nanometer-scale immune synapses in human tumor samples.
The dome structure appears linked to adhesion interactions and internal organization of the immune cell.
The study, published in Cell Reports on 1 April 2026, could guide development of improved immuno-oncology therapies.