Full Breakdown
Amy Schumer Discusses Botched Colonoscopy Amid Ongoing Health Transformations
5/19/2026, 4:43:28 AM
Botched Colonoscopy Disclosure
During the “Not Skinny But Not Fat” podcast, hosted by Amanda Hirsch for Dear Media, Amy Schumer announced that a recent colonoscopy was “botched.” She said the complication left her “not feeling very sexual,” while also stating she feels “happier than I’ve ever been before.” Sources list the event as occurring on either May 17 or May 18.
Health Background
Schumer disclosed a Cushing syndrome diagnosis linked to prior steroid injections, which led to a 50-pound weight loss. Earlier use of Ozempic and Wegovy caused severe gastrointestinal side effects. She now takes Mounjaro, noting better energy, skin, hair, and libido, and receives estrogen-progesterone therapy for perimenopause. She is separated from chef Chris Fischer and shares a seven-year-old son, Gene.
Timeline
2024 – Schumer announced a Cushing syndrome diagnosis in a newsletter. Early 2025 – She discussed the condition on the Call Her Daddy podcast and reported a 50-pound weight loss. 2025 – She described severe side effects from Wegovy and Ozempic, then began Mounjaro with reported improvements. Late 2025 – She announced separation from Chris Fischer. May 17/18 – She disclosed the botched colonoscopy at the Dear Media podcast.
Medical Interventions and Reported Effects
Schumer reports that Ozempic and Wegovy produced severe gastrointestinal distress, leading her to discontinue them. Mounjaro is credited with increased energy, fuller hair, clearer skin, and heightened libido. Estrogen-progesterone therapy resolved perimenopausal symptoms. The colonoscopy complication is described only as reducing sexual feeling, with no clinical details provided.
Implications
The disclosure highlights that procedural complications can affect sexual health, a topic rarely addressed publicly. Schumer’s openness may encourage patients using GLP-1 drugs or hormone therapy to discuss side effects. The remarks also intersect with personal stress from her separation, illustrating how life events can influence health perception.
Official Statements & Responses
Schumer herself stated she feels “happier than I’ve ever been before” despite the colonoscopy issue, confirmed that estrogen-progesterone therapy eliminated perimenopausal symptoms, and described Mounjaro as “great.” Her representatives declined to comment on the colonoscopy incident, per a Fox News request.
Conflicting Reports & Gaps
Sources differ on the exact date of the podcast appearance (May 17 versus May 18). No source provides details on the specific error that rendered the colonoscopy “botched,” leaving the medical nature of the complication unverified.
Verbatim Quotes
- “I feel happier than I’ve ever been before.” — Amy Schumer, Comedian and Actress
- “I actually had, kind of, a botched colonoscopy, so I’m not feeling very sexual.” — Amy Schumer, Comedian and Actress
- “I was getting these steroid injections, and so it gave me this thing called Cushing syndrome; which I wouldn’t have known if the internet hadn’t come for me so hard.” — Amy Schumer, Comedian and Actress
- “They put me on estrogen and progesterone because I realized I was in perimenopause and my symptoms of being in perimenopause have disappeared,” — Amy Schumer, Comedian and Actress
