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Bookmakers Release MLB Picks for May 20-21 Games

5/21/2026

27 4 Full Breakdown

Summary

Bookmakers Post Picks

U.S. bookmakers posted MLB betting picks for games on May 20-21, 2026.
The May 20 Red Sox-Royals line listed Royals –120, Red Sox +100, Royals –1.5 (+150) and a 7.5-run total.
The May 21 Rockies-Diamondbacks parlay set Arizona –1 and under 11.5 runs, noting the Diamondbacks were without Burnes, Puk and Martinez.
DFS salaries named Guerrero $4,700, Okamoto $3,600, Clement $3,200, Rodriguez $7,500, Severino $6,500, Carroll $5,400, Gelof $3,800.

Summary

Ohtani Dominates

Ohtani posted a 0.82 ERA in his first seven starts, the Dodgers’ second-lowest behind Fernando Valenzuela’s 0.29 ERA in 1981.
He is a +700 fifth-favorite for the NL Cy Young Award, behind Paul Skenes (+230).
Randy Vasquez, MLB’s third-most profitable pitcher, now averages a 94.9 mph fastball after working with Yu Darvish, with a $100 bet on each of his nine starts returning +596.

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Bookmakers Post Picks

U.S. bookmakers posted MLB betting picks for games on May 20-21, 2026.
The May 20 Red Sox-Royals line listed Royals –120, Red Sox +100, Royals –1.5 (+150) and a 7.5-run total.
The May 21 Rockies-Diamondbacks parlay set Arizona –1 and under 11.5 runs, noting the Diamondbacks were without Burnes, Puk and Martinez.
DFS salaries named Guerrero $4,700, Okamoto $3,600, Clement $3,200, Rodriguez $7,500, Severino $6,500, Carroll $5,400, Gelof $3,800.

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