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MRI Patterns Predict ADHD Trajectories Better Than Checklists

5/24/2026

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Story summary
  • Researchers led by Qiang Luo (Fudan University) examined MRI scans of 7,436 in Adolescent Brain Cognitive Development study.
  • After two years they classified youths as persistent, remitting or emergent.
  • Persistent, remitting and emergent youths showed distinct patterns: thinned in frontal cortex, grew left-hippocampus, and thinned slower in posterior cingulate.
  • A model using scans outperformed checklist predictions for ADHD severity at age thirteen, and medication use did not affect remitting trajectory.