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Amivantamab Shrinks Tumors in 42% of Refractory Head-Neck Cancer

5/31/2026

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Story summary
  • Amivantamab shrank tumors in 42% of refractory head and neck cancer patients.
  • The trial enrolled 102 patients with metastatic head and neck cancer at 55 hospitals in 11 countries.
  • Patients received subcutaneous injections every three weeks, with median overall survival of 12.5 months and progression-free survival of 6.5 months.
  • The treatment caused moderate side effects, led fewer than ten patients to stop therapy, and blocked EGFR and MET.