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Guava Juice Shows Promise in Reducing Anemia Among Indonesian Women

6/1/2026, 4:06:57 AM

Review of Hemoglobin Gains with Guava Juice

Review of 17 Indonesian studies, including 12 quantitative trials with 235 teenage girls and pregnant women, found that guava juice added to iron supplements raised hemoglobin by an average of 1.71 g/dL, 1.29 g/dL higher than iron alone. Gains were 1.52 g/dL for teenage girls and 1.84 g/dL for pregnant women.

Anemia Context and Vitamin C Role

Iron-deficiency anemia is common among teenage girls and pregnant women in low-income countries, lowering energy, cognition and maternal health. Vitamin C enhances non-heme iron absorption, and guava provides up to four times more vitamin C per 100 g than oranges, plus vitamin A, folate and fiber.

Researchers and Institutional Input

The review “Effect of guava juice intake on haemoglobin levels in Indonesian females” was authored by Javeria Mansoor, Farhan Munaf, Muhammad Umair, Muhammad Humza Sajjad, Faiza Ashfaque, Muhammad Bashir and Hamza Massab Rehman, and published in BMJ Nutrition, Prevention & Health (May 2026). Professor Sumantra Ray of the NNEdPro Global Institute for Food, Nutrition and Health provided commentary.

Study Design and Quantitative Findings

The review included 17 studies—15 quasi-experimental and 2 randomized trials. Six focused on teenage girls, eleven on pregnant women, and nine examined guava juice plus iron. Across 235 participants, hemoglobin rose on average 1.71 g/dL, a 1.29 g/dL advantage over iron alone.

Official Statements & Responses

The authors suggest adding guava juice to school meals and antenatal care, noting its low cost, cultural acceptance and fit with the UN Decade of Action on Nutrition. Professor Ray said the findings reinforce the known benefit of vitamin C-rich foods for iron supplementation.

Criticism & Limitations

All trials were conducted in Indonesia, limiting geographic relevance. Study designs varied, most were quasi-experimental with small samples, and no long-term follow-up was reported, leaving durability of hemoglobin gains uncertain.

Conflicting Reports & Gaps

Only two randomized trials were identified, creating uncertainty about reproducibility. The review provides no data on optimal dosing, side effects or duration of hemoglobin improvement after stopping guava juice.

Verbatim Quotes

  • “An increase of 1–2 g/dl may shift individuals from mild or moderate anemia to non-anemic categories, improving fatigue, cognitive function, and productivity outcomes,” — Researchers, BMJ Nutrition Review
  • “Integrating guava juice into school nutrition programs, antenatal care packages, or community health initiatives could represent a feasible approach to address mild-to-moderate anemia, aligning with the United Nations’ Decade of Action on Nutrition (2016–2025), which emphasizes dietary diversification and locally sourced nutrient-rich foods,” — Study authors
  • “This study builds on the established role of dietary sources high in vitamin C to enhance iron absorption and improve the effectiveness of iron supplementation,” — Professor Sumantra Ray, NNEdPro Global Institute
  • “But quasi-experimental research, the wide variation in study design, small sample sizes, and limited length of follow-up mean that caution is required when interpreting the findings.” — Professor Sumantra Ray

What’s Next: Research and Policy Recommendations

The authors call for rigorously designed randomized trials to define therapeutic dose, treatment length and long-term outcomes. Standardizing guava juice formulations, strengthening local supply chains and embedding the approach within public-health nutrition programs are priorities for scaling anemia control.