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Post-Surgery Delirium Accelerates Cognitive Decline in Seniors

6/8/2026

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Story summary
  • Researchers from Brown University reported postoperative delirium predicts faster cognitive decline in adults 70+.
  • The SAGES study tracked 560 participants with six-month tests for three years and annual tests for six years.
  • Delirium after surgery accelerated decline more than mild cognitive impairment.
  • Each rehospitalization correlated with decline but did not explain the delirium effect.
  • Patients with delirium had more rehospitalizations, a finding senior author Dr. Sharon K. Inouye called surprising.