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Life Biosciences Treats First Patient in Glaucoma Gene Therapy Trial

6/11/2026

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Story summary
  • U.S. biotech Life Biosciences treated the first patient in a glaucoma gene-therapy trial with ER-100.
  • ER-100 activates three genes to partially reprogram retinal ganglion cells.
  • ER-100 is delivered by a non-infectious virus that works only while patients take an antibiotic.
  • The FDA approved the trial on January 15 and will enroll up to 18 participants.
  • Chief scientific officer Sharon Rosenzweig-Lipson notes regeneration, warns of cancer and no reduction, making safety.