Story perspectives

Synthetic Psilocybin Reduces Suicidal Thoughts 75%, 45% Remission

6/14/2026

Summary

Story summary

Researchers gave 20 U.S. adults a 25-mg synthetic psilocybin dose and observed anti-suicidal effects.
By week three, 75% responded positively, with ideation scores dropping about 14 points.
Forty-five percent achieved full remission, with 14 of 20 in remission or near remission at three months.
No adverse events occurred, though participants reported nausea, headache and anxiety, and two showed increased ideation, one improving while the other stayed elevated at twelve weeks.

1 of 1

Story summary

Researchers gave 20 U.S. adults a 25-mg synthetic psilocybin dose and observed anti-suicidal effects.
By week three, 75% responded positively, with ideation scores dropping about 14 points.
Forty-five percent achieved full remission, with 14 of 20 in remission or near remission at three months.
No adverse events occurred, though participants reported nausea, headache and anxiety, and two showed increased ideation, one improving while the other stayed elevated at twelve weeks.