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PM2.5 Boosts Aortic Stenosis Risk 2.5-Fold, Study Finds

6/15/2026

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Summary

Story summary

Yaohua Tian led a 13-year U.K. study of nearly 500,000 adults that linked PM2.5 exposure to aortic stenosis.
The study recorded over 3,600 cases, finding a 60 % higher odds and more than 2.5 times the risk in most polluted areas.
High genetic risk doubled odds and, when combined with high pollution, raised risk four-to-sixfold.
A Chinese replication of more than 8 million adults for seven years showed the same directional association.

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Story summary

Yaohua Tian led a 13-year U.K. study of nearly 500,000 adults that linked PM2.5 exposure to aortic stenosis.
The study recorded over 3,600 cases, finding a 60 % higher odds and more than 2.5 times the risk in most polluted areas.
High genetic risk doubled odds and, when combined with high pollution, raised risk four-to-sixfold.
A Chinese replication of more than 8 million adults for seven years showed the same directional association.