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Obese GLP-1 Users Lose 560 Daily Steps

6/19/2026

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Story summary
  • At ENDO 2026 researchers reported that adults with obesity who began GLP-1 receptor agonists cut their daily steps and moderate-to-vigorous activity.
  • Using NIH All of Us data linked to Fitbit records, the study analyzed 1,950 participants, with 753 providing adequate wearable data.
  • Average steps fell from 5,047 to 4,487 and activity minutes dropped from 28 to 22, with the sharpest declines in men and those reporting joint or muscle pain.