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Story summary
- At ENDO 2026 in Chicago, researchers reported that DEHP-exposed male rats showed increased adult anxiety.
- Pregnant rats received daily DEHP from conception to weaning, after which their 70-day-old male offspring tested on a plus maze spent less time in open arms, more in closed arms, and froze more.
- A GABA agonist or testosterone given before testing reduced anxiety behaviors, showing reversal of DEHP-induced neuroendocrine changes, Professor Osvaldo Juan Ponzo said.
