Story perspectives

Joe Manganiello Announces ‘Bloodlines’ Memoir on Autoimmune Struggle

6/25/2026

Summary

Manganiello Announces Memoir

Actor Joe Manganiello announced his memoir Bloodlines, releasing October 13, 2026.
The seven-year autoimmune cascade attacked his skin, thyroid, lungs and digestive system, causing chronic pain and an undisclosed life-saving organ amputation.
Facing unclear medical guidance, Manganiello explored spirituality, shamanic rituals, pagan practices and ancient myths.
He says writing Bloodlines gave perspective on the ordeal, which he calls his most brutal yet greatest adventure.
Bloodlines is now available for pre-order.

Summary

Manganiello Releases Memoir

Joe Manganiello’s memoir Bloodlines releases in hardcover, Kindle e-book, and audiobook on October 13 2026.
Pre-orders opened on Amazon and other retailers as Simon & Schuster launches worldwide.
In 2025 Manganiello and Caitlin O’Connor moved from Los Angeles to Pittsburgh to reconnect with roots.
Manganiello disclosed he overcame alcohol addiction in his early twenties before his acting career began.
The couple publicly announced their engagement on Instagram in October 2025, confirming a June 2025 proposal.

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Manganiello Announces Memoir

Actor Joe Manganiello announced his memoir Bloodlines, releasing October 13, 2026.
The seven-year autoimmune cascade attacked his skin, thyroid, lungs and digestive system, causing chronic pain and an undisclosed life-saving organ amputation.
Facing unclear medical guidance, Manganiello explored spirituality, shamanic rituals, pagan practices and ancient myths.
He says writing Bloodlines gave perspective on the ordeal, which he calls his most brutal yet greatest adventure.
Bloodlines is now available for pre-order.

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