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Brain Cells Stay Near Ancestral Kin, Across Species

6/27/2026

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Story summary
  • U.S. researchers led by scientist Stan Kerstjens in Professor Anthony Zador’s lab reported that brain cells stay near their ancestral cells, forming a lineage-based positional system alongside chemical signals.
  • They built a scalable lineage-based model, first testing it with theoretical calculations and then with mouse brain gene-expression data.
  • Similar lineage patterns appeared in zebrafish, suggesting the mechanism works across species and could apply to other tissues, tumors, and AI systems.