Story perspectives

Only 0.4% Face >10% 10-Year Statin Muscle Disorder Risk

7/1/2026

Summary

Story summary

Researchers reported 0.4% of participants faced a 10-year statin-related serious muscle disorder risk above 10%.
They analyzed EHR of over 1.7 million adults aged 50 + (men) and 60 + (women) from 1998-2018 and built a model predicting 1-, 5-, and 10-year serious muscle disorder risk, finding incidence very low.
Yu-Ming Ni, MD, said the study offers personalized risk data to guide statin use.
Roger Blumenthal, MD, said lowering LDL-cholesterol clearly benefits patients.

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Story summary

Researchers reported 0.4% of participants faced a 10-year statin-related serious muscle disorder risk above 10%.
They analyzed EHR of over 1.7 million adults aged 50 + (men) and 60 + (women) from 1998-2018 and built a model predicting 1-, 5-, and 10-year serious muscle disorder risk, finding incidence very low.
Yu-Ming Ni, MD, said the study offers personalized risk data to guide statin use.
Roger Blumenthal, MD, said lowering LDL-cholesterol clearly benefits patients.