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Frog-Derived Bacteria Eradicate Mouse Colon Tumors 100%

7/14/2026

Summary

Story summary

An intravenous dose of the frog-derived bacterium Ewingella americana eradicated colorectal tumors in mice, achieving a 100 % complete response rate.
The bacteria multiplied about 3,000-fold in low-oxygen tumor zones within one day.
They cleared from blood in 24 hours, showing a 1.2-hour half-life and only mild inflammation.
Researchers at Japan Advanced Institute of Science and Technology will test the approach on solid tumors and combine it with chemotherapy or immunotherapy.

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Story summary

An intravenous dose of the frog-derived bacterium Ewingella americana eradicated colorectal tumors in mice, achieving a 100 % complete response rate.
The bacteria multiplied about 3,000-fold in low-oxygen tumor zones within one day.
They cleared from blood in 24 hours, showing a 1.2-hour half-life and only mild inflammation.
Researchers at Japan Advanced Institute of Science and Technology will test the approach on solid tumors and combine it with chemotherapy or immunotherapy.