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Fluoride-Free Gel Rebuilds Enamel, Set for 2025 Launch

7/24/2026

Summary

Story summary

Scientists at the University of Nottingham created a fluoride-free dental gel that rebuilds damaged enamel.
Dr. Abshar Hasan reported the protein-based gel mimics enamel proteins, draws calcium and phosphate from saliva and guides epitaxial mineralization.
Laboratory tests showed the regenerated enamel restored healthy architecture and behaved like natural enamel under simulated brushing, chewing and acidic foods.
Mintech-Bio aims to launch a commercial product next year for patients with enamel loss.

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Story summary

Scientists at the University of Nottingham created a fluoride-free dental gel that rebuilds damaged enamel.
Dr. Abshar Hasan reported the protein-based gel mimics enamel proteins, draws calcium and phosphate from saliva and guides epitaxial mineralization.
Laboratory tests showed the regenerated enamel restored healthy architecture and behaved like natural enamel under simulated brushing, chewing and acidic foods.
Mintech-Bio aims to launch a commercial product next year for patients with enamel loss.