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Insurers Restrict GLP-1s as Obesity Costs Surge, Safety Concerns Rise

7/25/2026

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Story summary
  • University of Mississippi researchers say insurers still restrict GLP-1 drugs such as Ozempic, Wegovy and Zepbound.
  • The Institute for Clinical and Economic Review finds GLP-1s cost-effective but over $821 million budget, and says Sujith Ramachandran warns the 40 % U.S. obesity rate could push insurer spending into billions despite no proof of long-term savings.
  • Doctoral candidate Liang-Yuan Lin warns compounded GLP-1s lack FDA approval and may contain unsafe ingredients.