Story perspectives

Leaf-Eared Mouse Hits 22,000 ft, Genes Boost Toxic-Plant Survival

7/26/2026

Summary

Story summary

Scientists found the leaf-eared mouse lives at up to 22,000 feet (6,700 m), the highest elevation for any mammal.
Genomic analysis of 167 mice showed high-altitude individuals retain stronger thermogenic capacity, energetic mitochondria and efficient brown-fat burning, with selection on antioxidant-defence and toxin-processing genes.
Guillermo D'Elía (Universidad Austral de Chile) said toxic high-elevation plants drove the toxin-processing adaptation, which Zachary Cheviron (University of Montana) said could aid treatment of low-oxygen cardiorespiratory disease.

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Story summary

Scientists found the leaf-eared mouse lives at up to 22,000 feet (6,700 m), the highest elevation for any mammal.
Genomic analysis of 167 mice showed high-altitude individuals retain stronger thermogenic capacity, energetic mitochondria and efficient brown-fat burning, with selection on antioxidant-defence and toxin-processing genes.
Guillermo D'Elía (Universidad Austral de Chile) said toxic high-elevation plants drove the toxin-processing adaptation, which Zachary Cheviron (University of Montana) said could aid treatment of low-oxygen cardiorespiratory disease.