Story perspectives

Study Finds 26 Fibromyalgia Genes, Highlights HTT Variant

7/28/2026

Summary

Story summary

Researchers published a Nature Medicine study identifying 26 genetic regions linked to fibromyalgia.
Using data from 2.5 million adults, 55 000 patients, they found the strongest risk variant in the HTT gene, another in GPR52, and most genes acting in brain pathways.
Researchers said genetics alone does not cause fibromyalgia and that triggers like arthritis are needed.
They launched the Chronic Pain Genomics Consortium to study chronic pain, beginning with pelvic pain.

1 of 1

Story summary

Researchers published a Nature Medicine study identifying 26 genetic regions linked to fibromyalgia.
Using data from 2.5 million adults, 55 000 patients, they found the strongest risk variant in the HTT gene, another in GPR52, and most genes acting in brain pathways.
Researchers said genetics alone does not cause fibromyalgia and that triggers like arthritis are needed.
They launched the Chronic Pain Genomics Consortium to study chronic pain, beginning with pelvic pain.