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High Court Clears Pathways Puberty-Blocker Trial for 220 Children

8/1/2026

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Story summary
  • High Court judge Justice Chamberlain dismissed a challenge, permitting the Pathways puberty-blocker trial to proceed.
  • King's College London will recruit over 220 children aged 11-16 starting 1 August, with half receiving medication immediately and half a year later.
  • Although the NHS England-commissioned, HRA- and MHRA-approved study drew warnings of inadequate safeguards, the judge said each child will be assessed for months by doctors who see a prospect of benefit.