Story perspectives
COVID-19 Linked to White-Matter Damage and Gray-Matter Loss
8/8/2026
1 of 1
Story summary
- Researchers reviewed 49 MRI studies that compared COVID-19 patients with healthy controls.
- The review found abnormal white-matter diffusion suggesting myelin damage even in mild cases.
- It also identified gray-matter loss and cortical thinning in the frontal, temporal and parietal lobes of recovered patients.
- Authors note reliance on cross-sectional data without baseline scans and call for unbiased longitudinal whole-brain research.
