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COVID-19 Linked to White-Matter Damage and Gray-Matter Loss

8/8/2026

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Story summary
  • Researchers reviewed 49 MRI studies that compared COVID-19 patients with healthy controls.
  • The review found abnormal white-matter diffusion suggesting myelin damage even in mild cases.
  • It also identified gray-matter loss and cortical thinning in the frontal, temporal and parietal lobes of recovered patients.
  • Authors note reliance on cross-sectional data without baseline scans and call for unbiased longitudinal whole-brain research.