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Full Breakdown

Multi-Vehicle Crash on U.S. Highway 281 Leaves Two Children Seriously Injured

8/17/2026, 11:47:14 AM

Crash Overview

On Saturday afternoon, a three-vehicle collision occurred on the northbound lanes of U.S. Highway 281 near Bitters Road in San Antonio. The San Antonio Police Department (SAPD) reported that a Toyota Highlander traveling on an access road experienced a medical episode, causing the driver to lose control. The Highlander struck a sign, crossed onto the main highway, and collided with a Dodge Ram. The impact forced the Ram into a Chevrolet Suburban, after which the Ram rolled several times.

Sequence of Events and Vehicle Details

  • Toyota Highlander: Lost control after driver’s medical episode; struck a sign before entering the main lanes.
  • Dodge Ram: Hit by the Highlander, then slammed into the Chevrolet Suburban and rolled multiple times.
  • Chevrolet Suburban: Struck by the Ram as it rolled.

SAPD’s preliminary report places the initial loss of control at approximately 3:30 p.m. Officers on scene confirmed that the driver of the Ram, a 40-year-old man, sustained non-life-threatening injuries.

Injuries and Medical Response

Two female passengers in the Ram, aged 15 and 11, were ejected during the rollover. Both were initially classified as having life-threatening injuries. KSAT later noted that the 11-year-old’s condition had improved to non-life-threatening, while the 15-year-old suffered a broken ankle. All three occupants—driver and two children—were transported to a local hospital for treatment.

Road Closure and Investigation

The crash prompted the closure of northbound U.S. Highway 281. SAPD kept the highway shut for several hours, reopening all lanes around 6 p.m. The department continues to investigate the incident, and the driver of the Highlander remained at the scene and is cooperating with investigators.

Impact on the Community

The accident disrupted traffic flow for several hours and highlighted the potential consequences of sudden medical emergencies while driving. Emergency responders emphasized the importance of rapid medical attention for ejected occupants, and local officials reiterated ongoing efforts to improve roadway safety.