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L-BAIBA boosts muscle function in mice, study finds

8/18/2026

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Story summary
  • University of Leeds researchers identified L-?-aminoisobutyric acid (L-BAIBA) as a muscle-signaling molecule in a Nature Communications paper on August 18, 2026.
  • In mice, L-BAIBA (but not its D-form) enlarged muscles, improved function, increased fatigue resistance and protected obese and type-2 diabetic mice from weakness.
  • Human studies linked higher circulating L-BAIBA to fitness and post-exercise rises.
  • Professor Lee Roberts said therapy is distant and urged regular aerobic activity.