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Trey Mancini Retires After Stage 3 Colon Cancer Return

8/18/2026

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Summary

Story summary

Trey Mancini announced his retirement on Instagram on Tuesday.
He played eight MLB seasons, winning the 2022 World Series with the Astros.
After a Stage 3 colon cancer diagnosis in March 2020, he had surgery and chemotherapy, returned in 2021, earned the AL Comeback Player of the Year Award and rejoined MLB with the Angels in June.

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Story summary

Trey Mancini announced his retirement on Instagram on Tuesday.
He played eight MLB seasons, winning the 2022 World Series with the Astros.
After a Stage 3 colon cancer diagnosis in March 2020, he had surgery and chemotherapy, returned in 2021, earned the AL Comeback Player of the Year Award and rejoined MLB with the Angels in June.