Story perspectives
Moderna and Merck’s Intismeran Plus Keytruda Cuts Melanoma Recurrence
8/20/2026
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Story summary
- Moderna and Merck announced Intismeran plus Keytruda cut melanoma recurrence in a trial.
- The trial enrolled 1,137 melanoma patients receiving nine vaccine doses plus Keytruda or Keytruda alone.
- Interim results met the primary goal of longer recurrence-free survival and secondary goal of reduced metastasis.
- Moderna shares rose 175% to $154.48 while Merck shares gained about 11%.
- Data will be presented at an international medical meeting as companies discuss regulatory filings.
