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Moderna and Merck’s Intismeran Plus Keytruda Cuts Melanoma Recurrence

8/20/2026

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Story summary
  • Moderna and Merck announced Intismeran plus Keytruda cut melanoma recurrence in a trial.
  • The trial enrolled 1,137 melanoma patients receiving nine vaccine doses plus Keytruda or Keytruda alone.
  • Interim results met the primary goal of longer recurrence-free survival and secondary goal of reduced metastasis.
  • Moderna shares rose 175% to $154.48 while Merck shares gained about 11%.
  • Data will be presented at an international medical meeting as companies discuss regulatory filings.