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Moderna and Merck’s Keytruda Combo Extends Melanoma Recurrence-Free Survival

8/22/2026

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Story summary
  • Moderna and Merck reported their vaccine-Keytruda combo reduced melanoma recurrence in a Phase 3 trial.
  • The study enrolled 1,137 high-risk stage IIB-IV melanoma patients who had surgery.
  • Patients receiving the combo achieved longer recurrence-free survival.
  • The combo also met the secondary endpoint of distant metastasis-free survival.
  • Side effects were mild to moderate with no new safety concerns.