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DRC starts EBO-PEP trial for high-risk Ebola contacts

9/6/2026

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Story summary
  • The Democratic Republic of Congo has launched the EBO-PEP trial to treat high-risk Ebola contacts, focusing on children.
  • Since mid-May, the outbreak has killed over 3,000 people, with children under five experiencing over 60% mortality.
  • The protocol now allows children weighing over 20 kg to receive experimental antiviral obeldesivir, while those under 20 kg remain excluded.
  • Remdesivir is an alternative for under-20 kg children, but its 10-day IV infusion is difficult during outbreaks.