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Story summary
- Researchers identified a novel “nose-to-brain circuit” that links nasal breathing to anxiety regulation in mice.
- Slow nasal breathing lowered anxiety-like behavior more than slow mouth breathing in the rodents.
- Low-frequency nasal airflow reduced anxiety, whereas high-frequency airflow increased it.
- Silencing the olfactory-bulb-to-perirhinal-cortex pathway eliminated the airflow-frequency effect on anxiety.
- A two-week regimen of slow nasal airflow restored neural activity and further reduced anxiety-like behaviors.
