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Story summary
- Taylor Fritz lost to Francisco Cerundolo in the US Open third round after leading by two sets.
- Jannik Sinner missed the US Open because of injury.
- Carlos Alcaraz returned to the tournament after a long lay-off.
- Six of the top-10 seeds were eliminated by the fourth round at Flushing Meadows.
- Remaining top-10 seeds are Alexander Zverev, defending champion Alcaraz and Ben Shelton.
