CDC Reports Nationwide Rise in Rabies Exposures and Vaccine Use

In early September 2026 the U.S. Centers for Disease Control and Prevention (CDC) issued a health advisory after a 17 % increase in rabies-related inquiries during July and August compared with the same period in 2025. At least eight state health departments have reported higher numbers of post-exposure treatments or administration errors. The CDC emphasized that prompt administration of rabies vaccine and human rabies immune globulin remains critical for effective protection.

CDC reports increase in rabies-related inquiries across the U.S. UsNews and World Report

Pharmacy data compiled through early September show a 33 % rise in use of the two rabies vaccines licensed in the United States and a 76 % increase in the two rabies immune-globulin products, relative to the previous year. The CDC confirmed that supplies of both vaccine and immune globulin are adequate and not experiencing shortages.

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Rabies spreads through bites, scratches, or contact with infected saliva and is almost always fatal once symptoms appear. The CDC recommends that anyone bitten or scratched seek immediate medical care. For individuals without prior vaccination, the regimen includes one dose of immune globulin placed around the wound plus four vaccine doses on days 0, 3, 7, and 14. Previously vaccinated persons receive two vaccine doses on days 0 and 3, without immune globulin. Those with weakened immune systems may require an additional dose and serologic testing to confirm immunity. Health officials assess the likelihood of rabies based on animal species, regional prevalence, behavior, and wound severity; observation of the animal for 10 days or a negative test can obviate treatment.

UsNews and World ReportCDC reports increase in rabies-related inquiries across the U.S.

Approximately 4 million Americans seek medical care after animal contact each year, and roughly 100 000 receive rabies post-exposure prophylaxis. Fewer than 10 deaths occur annually in the United States. Wildlife accounts for more than 90 % of the roughly 4 000 animal rabies cases reported each year, with bats, raccoons, skunks and foxes being the most common carriers. The CDC advises avoiding wildlife, keeping pets up to date on rabies vaccination, and washing any bite or scratch with soap and water for at least 15 minutes before contacting a health provider.

UsNews and World ReportCDC reports increase in rabies-related inquiries across the U.S.