1 of 1
Story summary
- US researchers found cefepime associated with higher all-cause mortality than other beta-lactam antibiotics.
- The meta-analysis included 110 randomized trials with over 22,000 patients receiving cefepime or another beta-lactam.
- Cefepime patients experienced 778 deaths (6.6%) versus 6.2% in comparator groups.
- Bayesian analysis gave a 94.4% probability cefepime raises mortality, increasing to 98.6% in peer-reviewed studies.