Back to today’s briefing

Story perspectives

New Gold Standard for Gene Therapy Measurements Revealed

1/7/2025

47 11

Summary

Story summary

Researchers have scrutinized gene therapy measurement techniques, particularly for adeno-associated viruses (AAVs). They discovered that the PCR-ELISA method fell short in accuracy and precision, while size exclusion chromatography with multi-angle light scattering (SEC-MALS) emerged as the gold standard. The team is now focused on creating standardized procedures to enhance measurement reliability in future studies.

1 of 1

Story summary

Researchers have scrutinized gene therapy measurement techniques, particularly for adeno-associated viruses (AAVs). They discovered that the PCR-ELISA method fell short in accuracy and precision, while size exclusion chromatography with multi-angle light scattering (SEC-MALS) emerged as the gold standard. The team is now focused on creating standardized procedures to enhance measurement reliability in future studies.